ADCs are potent and specific biopharmaceuticals. ADCs combine the specific targeting abilities of an antibody with a cytotoxin that attacks only the cancer cells that contain a unique marker. Many ADCs utilize DM1 as the warhead linked with an antibody by SMCC. Typically plasma is collected for ADC bioanalysis which requires the subject to spend hours at a clinic. This regime is often inconvenient for stage three subjects affected by aggressive cancer. Convenient and accurate sample collection at home is possible using the MMD. MMD allows for accurate and precise self collection of a blood sample with only a finger prick. DM1 and DM1-MCC collected on MMD were extracted and analyzed by HPLC-MS/MS.

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