PharmSci 360

October 25, 2020

Ernest N. Morial Convention Center
New Orleans, LA

Applied Pharmaceutical Analysis 2020

October 11, 2020

Boston, MA

TIDES: Oligonucleotide and Peptide Therapeutics - Virtual Presentation

September 15, 2020

Poster Presentation: A Universal Method for the Quantitation of Multiple Oligonucleotides from Plasma by MFLC-MS/MS (Abstract)

Microsampling of Non-Invasive Matrices: Practical Examples Using Tears and a Perspective of Past and Emerging Technologies

July 13, 2020

Presented by Jason Watts, PhD, virtually at the AAPS Land O' Lakes Bioanalytical Conference. 

Non-invasive matrices such as tears, sweat, saliva, and milk offer an enticing alternative to traditional sampling from blood, serum, and plasma.  Collection of these matrices is simpler and more affordable than venipuncture, as well as being much less unpleasant for patients and study subjects allowing for more frequent sampling, higher compliance, and removal of fear of needles as a barrier to clinical trial recruitment. However, bioanalysis of these matrices is not without challenges. Sample volumes can be very low, the more complex matrices such as milk may require extensive sample preparation, and the use of the matrix must be biologically relevant. Using the example of a method we developed at Alturas Analytics Inc. to measure Tobramycin from human tears, we will discuss practical applications of microsampling of non-invasive matrices for bioanalysis, and improvements offered by emerging technologies.

Land O'Lakes 21st Annual Bioanalytical Conference

July 13, 2020

Presentation: Microsampling of Non-Invasive Matrices: Practical Examples Using Tears and a Perspective of Past and Emerging Technologies (Abstract)
Presented by Jason Watts, PhD

Virtual Presentation