Thyroid hormones are critical regulators of metabolism, growth, and development. Thyroxine (T4) and 3,3’,5-triidothyronine (T3) are produced in the thyroid gland and released into circulation where the more biologically active form, T3 exerts effects on peripheral tissues. The serum level of T4 is a useful biomarker of overall thyroid function. Low or high levels of circulating thyroid hormones are indicative of thyroid or pituitary gland dysfunction resulting from disease or malnutrition. Hyperthyroidism or hypothyroidism can result from autoimmune disorders, such as Graves’ disease, certain medications, thyroid cancer, and can often occur during pregnancy. Individuals suffering from thyroid dysfunction suffer from a broad range of symptoms including weakness and fatigue. The Mitra® Microsampling Device (MMD) enables convenient and accurate at-home sample self-collection from a simple finger prick