Presentations

Archive of Presentations by the Alturas Research Team

Presentations

Optimized Extraction and MFLC-MS/MS Analysis of the Antibody Drug Conjugate SigmaMAb Extracted from Rat Plasma - (abstract)
— To be presented at AAPS PharmSci 360, November 4-7, 2018, Washington, DC

Sharing Scientific Data in the Public Domain: A Panel Discussion 
— Bioanalysis Zone Panel Discussion, Chaired by Amanda Wilson (AstraZeneca), with Industry Leaders Shane Needham (Alturas Analytics), Jason Wrigley (Merck KGaA), Melanie Anderson (Merck), Lawrence Goo (KCAS), Patrick Liu (Teva pharmaceuticals)
(Watch On Demand)


Quantitative Microflow HPLC-MSMS Analysis of the Antibody Drug Conjugate SigmaMAb Extracted from Rat Plasma
- view abstract
— Presented at the 66th ASMS Conference on Mass Spectrometry and Allied Topics, June 2018, San Diego, CA


Multiplex Screening for Cystine-Dense Peptides (CDP) Therapeutics Proteins by HPLC-MS/MS
- view abstract  
— Presented at TIDES: Oligonucleotides and Peptide Therapeutics, May 2018, Boston, MA


A Connected Workflow in the Bioanalytical Lab
— Presented at the European Symposium on Clinical & Pharmaceutical Solutions through Analysis (CPSA) Symposium Session 5, February 8th, 2018, 10:15, Cambridge, UK
Video File of presentation


Microspray and Microflow Liquid Chromatography: The Perfect Fit for Modern LC-MS Bioanalysis 
— Presented at 13th Boston Society APA and APS Conference, September 2017, Providence, RI

Using Real-Time Watson LIMS Data Integration and Analytics to Monitor Data Quality and Productivity, an Application of the Business Integration Program in the Bioanalytical Lab 
— Shane Needham, Ph.D., and Ann Hoffman

Quantitative HPLC-MS/MS Analysis of DM1 and DM1-MCC Extracted from Whole Blood Dried onto a Mitra® Microsampling Device  
— Presented at ASMS, June 2017, Indianapolis, IN

 The Evaluation of Noviplex Plasma Prep Cards for Regulated Bioanalysis  
— Presented at AAPS, November 2016, Denver, CO 

Quantitative Analysis and Protein Binding Determination of fXa Inhibitors in Human Plasma containing Adexanet Alfa by HPLC-MS/MS    
— Presented at ASMS, June 5-9, 2016, San Antonio, TX

Performance of a Selective Method for Quantitation of Midazolam & its Metabolite, Developed to Monitor Drug-Drug Interactions in the Presence of Coadministered Drugs
— Presented at ISSX, Oct. 18-21, 2015, Orlando, FL

Quantitative Analysis of Cotinine in Human Plasma and Urine Utilizing a Simple Supported Liquid/Liquid Exchange Extraction and GC-MS/MS  
— Presented at ASMS, May 31-June 4, 2015, St. Louis, MO

Effects of Matrix Age on Protein Binding Results Extracted with a Prototype Phospholipid Removal Plate and Analyzed using MFLC-MS/MS 
— Presented at ASMS, June 9-13th, 2013, Minneapolis, MN

Utilizing MFLC-MS/MS for Large Molecule Quantitative Bioanalysis 
— Presented at ASMS, June 9-13th, 2013, Minneapolis, MN

Comparison of MFLC-MS/MS Validation Data of Methotrexate in Human Plasma to Conventional HPLC-MS/MS  
— Presented at AAPS, October 14-18th, 2012, Chicago, IL

Dextromethorphan Metabolism Profiling by the Analysis of Dried Matrix Samples Collected from Liver Microsomes In-Vitro Fluid and Analyzed by MFLC MS/MS
— Presented at ASMS, May 23-26th, 2012, Vancouver, BC, Canada

Quantitative Analysis of Hydrazine and Acetylhydrazine Using Chemical Derivatization and HPLC-MS/MS
— Presented at ASMS, May 23-26th, 2012, Vancouver, BC, Canad

Comparison of Traditional HPLC/MS/MS and Micro Flow LC/MS/MS Sensitivity for Large Molecule Detection
— Presented at NBC, May 21-23rd, 2012, San Diego, CA

Automated DBS Extractions in Liquid Handling Dispensing Tips and Internal Standard Addition Using Conventional Bioanalytical Instruments  
— Presented at AAPS Meeting, October 23-27th, 2011, Washington, DC

Comparison of Traditional HPLC-MS/MS Sensitivity to the Sensitivity of Micro Flow Liquid Chromatography-MS/MS
— Presented at ASMS Meeting, June 5-9th, 2011, Denver, CO

Overcoming the Obstacles of Performing Dilutions and Internal Standard Addition to DBS Analysis Using HPLC/MS/MS
— Presented at ASMS Meeting, June 5-9th, 2011, Denver, CO

The Use of Conventional Bioanalytical Instruments to Automate DBS in Liquid Handling Dispensing Tips
— Presented at DIA Meeting, May 3-4th, 2011, Philadelphia , PA

Determination of Fluconazole in Human CSF Using Dried Blood Spot Technique and HPLC/MS/MS
— Presented at AAPS 2010, New Orleans, LA

Dried Matrix Spot Tears
— Presented at APA Conference 2010 

Validation of an HPLC/MS/MS Bioanalytical Method for the Quantitative Analysis of Lidocaine from Rat and Mini-Pig Plasma
— Presented at ASMS 2010

Dried Blood Spot Analysis – Utilizing the Technique to Develop Assays in Rare or Limited Matrices 
 Presented at ASMS 2010

Validation of an HPLC/MS/MS Bioanalytical Method for the Quantitative Analysis of Lidocaine from Rat and Mini-Pig Plasma 
 Presented at ISSX 2009

Dried Blood Spot Sampling in the Pharmaceutical Industry 
 Presented at DIA/PhRMA Workshop, Dec 8, 2009 

Stabilization of a Peptide for Validation of HPLC/MS/MS Methods for the Quantitative Analysis of Peptides from Blood and Plasma 
— Presented at ASMS 2008

Method Development and cGLP Validation for the HPLC/MS/MS Bioanalysis of Vancomycin Extracted from Rat Plasma
— Presented at ASMS 2008

Development of a Bioanalytical LC/MS/MS Assay for the Quantitative Analysis of Amikacin, Neomycin and Gentamicin in Plasma and Tissue Samples
— Presented at ASMS 2008

Validation of an HPLC/MS/MS Bioanalytical Method for the Quantitative Analysis of Alprazolam, α-OH-Alprazolam and 4-OH-Alprazolam in Human Plasma
— Presented at ASMS 2006

Validation of a Chiral HPLC/MS/MS Bioanalytical Method for the Quantitative Analysis of the Enantiomers of Ketaconazole in Human and Dog Plasma
— Presented at ASMS 2006

Validation of an HPLC/MS/MS Bioanalytical Method for the Quantitative Analysis of Loxapine, Amoxapine, 7-OH-Loxapine and 8-OH-Loxapine in Human Plasma
— Presented at ASMS 2006

Development of a Novel HILIC HPLC/MS/MS Bioanalytical Method for the Quantitative Analysis of Carboplatin from the Plasma of Mouse
— Presented at ASMS 2005

Development of an HPLC/MS/MS Bioanalytical Method for the Quantitative Analysis of a Polypeptide Proteinase Inhibitor from Plasma
— Presented at ASMS 2004 

HPLC/MS/MS Quantitative Bioanalysis Used in Homeland Security and Anti-Terrorism Efforts: Analysis of Atropine Used to Protect Against Chemical Warfare Agents
— Presented at ASMS 2003, Montreal QC, Canada

Development of an HPLC/MS/MS Method for the Quantative Bioanalysis of Vancomycin from the Plasma of Several Species: A Lesson Learned When Conventional Methods Are Unsuccessful
— Presented at ASMS 2003, Montreal, QC, Canada 

Method Validation for the Simultaneous HPLC/MS/MS Quantitation of Midazolam and 1-Hydroxymidazolam in Human Plasma
— Presented at ASMS 2002, Orlando, FL

A Novel Method for the HPLC/MS/MS Quantitative Analysis in Guinea Pig and Mouse Plasma of Pyridostigmine, a Pretreatment Compound for Chemical Warfare Agents
— Presented at ASMS 2002, Orlando, FL 

GLP Validation in Guinea Pig Plasma of an HPLC/MS/MS Method for the Quantitative Analysis of Pyridostigmine, a Pretreatment Compound for Chemical Warfare Agents
— Presented at AAPS 2002